“Kansas City, Omaha, Des Moines, Minneapolis and Duluth could all receive several inches of snow,” said AccuWeather meteorologist Tyler Roys.
The Weather Channel warned that the Washington D.C., Baltimore and Philadelphia metro areas will see accumulating snow to start before it changes to a mix of sleet, freezing rain and then rain. That could make the Wednesday morning commute in those cities hazardous.
Freezing rain and ice will be especially dangerous in the mountains of West Virginia, Virginia and North Carolina, weather.com said, causing tree damage and scattered power outages. Lighter amounts of ice are forecast for portions of Indiana, Ohio and Pennsylvania.
In the South, several rounds of heavy, flooding rainfall and even some severe thunderstorms are expected Tuesday and Wednesday.
Up to a half foot of rain could swamp much of northern Mississippi, northern Alabama and Tennessee, where flood watches and warnings have been posted.
Summer will continue to pay an early visit to Florida on Tuesday as temperatures soar into the 80s. Several Florida cities set record highs Monday, including Vero Beach, which tied an all-time February record high of 89 degrees.
The unusual warmth is expected to continue in the Sunshine State for most of the week.
This article originally appeared on USA TODAY: Buckle up and hunker down: Coast-to-coast storm to bring weather misery to 200 million